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The Treasury is not "the enemy of Brexit", Chancellor of the Exchequer Philip Hammond has insisted.
In a speech in the City of London, Mr Hammond mentioned the UK wanted to guard patterns of commerce with the EU that had been "built over decades".
The chancellor additionally used his Mansion House speech to verify taxes must go as much as increase spending on the NHS.
But he mentioned the improve could be partly funded by decrease contributions to Brussels post-Brexit.
In the previous the chancellor has come beneath hearth from supporters of Brexit.
Earlier this month Foreign Secretary Boris Johnson referred to as the Treasury "the heart of Remain", in feedback to a non-public dinner.
However, addressing a City viewers on Thursday, Mr Hammond mentioned the "immediate key" to the UK and London's financial success was "ensuring we get a good Brexit deal".
He mentioned the purpose was a partnership that "recognises that our European neighbours are our most important trading partners, and that Dover to Calais is the busiest trading corridor in Europe".
As the UK leaves the EU, he mentioned the new relationship ought to "maintain low friction borders and open markets".
He went on: "That does not make the Treasury, on my watch, 'the enemy of Brexit'; rather, it makes it the champion of prosperity for the British people outside the EU, but working and trading closely with it."
Mr Hammond additionally mentioned the £20bn five-year NHS funding bundle introduced by the prime minister this week could be partly funded by decrease contributions to Brussels.
However, he additionally mentioned the authorities would keep on with its fiscal guidelines and "continue to reduce debt".
As a consequence taxpayers must "contribute a bit more", he additionally mentioned.
Earlier this week, Prime Minister Theresa May introduced a increase in NHS spending, which is able to see NHS England's price range improve by £20bn by 2023.
The plan additionally means more cash shall be given to the relaxation of the UKabout £4bnthough will probably be as much as the Welsh and Scottish governments to resolve how that's spent.
Mr Hammond mentioned the NHS was the authorities's "number one priority for the forthcoming spending review".
"So, as the Prime Minister said, taxpayers will have to contribute a bit more, in a fair and balanced way, to support the NHS that we all use."