Following the incidence, about 100 youths protested the killing and eventually dumped the bodies of two of the victims in front of the police station along Eket Oron Road.
An indigene of the area, who pleaded for anonymity, said that two other persons shot by the police were rushed to the hospital, but died on the way.
The aggrieved youths disrupted activities in some parts of Eket. The protest caused traffic gridlock.
Shops were forced to close as the aggrieved youths, with cutlasses and other weapons in their hands, matched to the police station.
However, Akwa Ibom State Police Public Relation Officer (PPRO), Mr. Etim Dickson, denied that the victims were killed by the police.
Dickson said that more security operatives had been deployed to calm the situation.