Manchester United will move into the top four with a win against West Ham United, but Slaven Bilicβs men will be determined to record a famous victory in what will be the last ever match to be contested at Upton Park.
The visitors will again be without top scorer Anthony Martial, who limped out of the warm-up ahead of Saturday's 1-0 victory against Norwich City.
Marcus Rashford was rested for the win at Carrow Road, but, in light of Martial's continued absence, the teenage sensation seems likely to return to the fold for Tuesday's tussle.

Rashford bagged the opening goal in last month's FA Cup quarter-final replay between the two teams at Upton Park and the 18-year-old front man is chalked up as a 11/2 (6.50)
- Goal